Dynamic Changes of Coagulation System Following Radiofrequency Catheter Ablation and Effect of Molecular Weight Heparin
- VernacularTitle:60例射频导管消融术后机体凝血系统活性的动态变化及低分子肝素的影响
- Author:
Yongquan PENG
;
Xiping ZHOU
;
- Publication Type:Journal Article
- Keywords:
Catheter ablation;
Radiofequency current;
Coagulation system;
Low molecular weight heparin
- From:
Chinese Circulation Journal
2004;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the dynamic changes of coagulation system following radiofrequency catheter ablation(RFCA) and effect of molecular weight heparin. Methods:Blood samples were collected at 6 different times to measure the thrombin-antithrombinⅢcomplex (TAT) and hepatocyte growth factor (HGF) in 60 RFCA candidates and 22 controls undergoing electrophysiological study (EPS).Patients were randomly divided into 2 groups.Low molecular weight heparin was given to 31 pationts (subgroup B) after RFCA,but not to the others (subgroup A). Results:①Plasma TAT exhibited a double peaked pattern in the subgroup A.The first peak occurred instantly after RFCA (42.8?15.7 ng/ml),and the second 3 days later (20.1?19.4 ng/ml).The second peak was significantly higher than that of the control group (2.7?1.5 ng/ml) and the subgroup B(4.3?5.2 ng/ml)(P
