Postoperative intraportal vein antieoagulation in the prevention of portal vein thrombosis in portal hypertensive patients
- VernacularTitle:肝硬化门静脉高压症分流加断流术后门静脉内抗凝预防血栓形成
- Author:
Li-Hua WANG
;
Wei LU
;
Gui-Juan SHEN
;
Yao-Sheng YU
;
Yong-Hua ZHUGE
;
Ya-Guo HU
;
Xian-Qing WU
;
Tian-sheng XU
- Publication Type:Journal Article
- Keywords:
Hypertension,portal;
Thrombosis;
Anticoagulation;
Splenorenal shunt,surgical
- From:
Chinese Journal of General Surgery
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical significance of intraportal vein anticoagulation for the prevention of portal vein thrombosis after portaazygous devascularization and splenorenal shunt. Methods In this study 67 patients of portal hypertension undergoing surgery were randomly divided into two groups,receiving respectively intraportal vein heparin injection by 100 U?kg~(-1)?d~(-1)?7 d in group A (32 patients)and placebo in group B(35 patients).Portal vein thrombosis,the recurrent bleeding after operation and portal hypertensive gastropathy were compared between the two groups.Results The occurrence of portal vein thrombosis after operation in group A(0)was significantly lower than that in group B(20%,X~2=5.169,P
