Arterial blood gas changes induced by CO_2 pneumoperitoneum in rabbits with lung and liver impact injury under controlled hemorrhage
- VernacularTitle:肝肺撞击伤伴失血后CO_2气腹对兔动脉血气影响的实验研究
- Author:
Yong LI
;
Lian-Yang ZHANG
;
Song ZHAO
;
- Publication Type:Journal Article
- Keywords:
Wounds and injuries;
Pneumoperitoneum;
Animal experimentation;
Blood gas analysis
- From:
Chinese Journal of General Surgery
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate arterial blood gas(ABG)changes induced by different intra- abdominal pressures during CO_2 pneumoperitoneum in rabbits with lung and liver impact injury under controlled hemorrhage.Methods In this study 75 rabbits were randomized into nine groups(6 rabbits in each group)according to the amount of blood loss(6 ml/kg、12 ml/kg、22 ml/kg)and intra-abdominal pressures(5 mm Hg,10 mm Hg,15 mm Hg).After model was established successsfully,respiratory rates (RR),ABG and death rates were observed at pre-pneumoperitoneum,after 0.5 hour and 2 hours under pneumoperitoneum and 0.5 hour after desufflation.Results Without pneumoperitoneum,different blood loss exerted different effect on arterial blood gas:RR,PaCO_2 increased(P
