Impact of risk factors on the severity of esophageal mucosal injury in patients with gastroesophageal reflux disease
- VernacularTitle:胃食管反流病食管黏膜损伤程度的影响因素
- Author:
Sui PENG
;
Jin-Kun LIN
;
Ying-Lian XIAO
;
An-Jiang WANG
;
Wei CHEN
;
Pin-Jin HU
;
Min-Hu CHEN
- Publication Type:Journal Article
- Keywords:
Gastroesophageal reflux disease;
Hiatal hernia;
Esophagitis
- From:
Chinese Journal of Digestive Endoscopy
1996;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the risk factors that could influence the severity of esophageal inju- ry in patients with gastroesophageal reflux disease(GERD).Methods GERD patients diagnosed on the ba- sis of endoscopic reflux esophagitis or pathological results of 24 hour esophageal pH monitoring were divided into three groups as non-erosive reflux disease group(NERD)(n=83),mild esophagitis group(n=51) and severe esophagitis group(n=22).The clinic data and esophageal pH parameters were recorded in the three groups.A logistic regression was used to assess the joint influences of clinic characteristics,hiatus her- nia,and esophageal pH parameters on the severity of esophageal injury.Results Patients in severe esoph- agitis group were more likely to have advanced age and hiatus hernia.The number of supine long reflux epi- sodes measured by esophageal pH monitoring significantly increased with increasing grades of mueosal dam- age(P
