Changes of Blood Lipid,Blood Rheology and Microcirculation of Model Rats of Diabetes Ⅱ with Heart Blood Stasis Syndrome
- VernacularTitle:2型糖尿病心血瘀证模型大鼠血脂、血液流变学、微循环的变化
- Author:
Meng-Zhou XIE
;
Hao-Mei TIAN
;
Chu-Tao CHEN
;
- Publication Type:Journal Article
- Keywords:
DiabetesⅡwith heart blood stasis syndrome;
Model rats;
Blood fat;
Blood rheology;
Microcireulation
- From:
Journal of Traditional Chinese Medicine
1992;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relations among blood lipid,blood rheology and microcirculation of bulbar conjunctiva of model rats of diabetesⅡwith heart blood stasis syndrome.Methods The rats were fed with high fat and caloric feed.Intraperitoneal injection of streptozotocin(STZ)in small dosage was applied to make the model of diabetesⅡ.Then the model of heart blood stasis syndrome was made through introperitoneal injecting dexamethasone and adrenalin.Eight hours after empty stomach,the rats were anaesthetized to measure the microcireulation of bulbar conjunctiva and test the blood lipid and carotid blood rheology.Results The indices of blood lipid,blood rheology and bulbar eonjunetiva microcirculation of model rats were all changed to abnormal,tallying with the changes of cardiovascular complications of diabetes.