Expression of cytokines in CD8~+ T lymphocytes of the peripheral blood of patients with condyloma acuminatum
- VernacularTitle:尖锐湿疣患者外周血CD8~+T细胞细胞因子的表达
- Author:
Dong-Xian LIU
;
Wen JIANG
;
Xing-Ping CHEN
;
Ying-Ling CHEN
;
Dong-Liang YANG
;
- Publication Type:Journal Article
- Keywords:
Condylomata acuminata;
CD8 positive T-lymphocytes;
Cytokines
- From:
Chinese Journal of Dermatology
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect the levels of cytokine IL-2,IL-12,IFN-?and IL-4 secreted by peripheral CD8~+ T lymphocytes in patients with condyloma acuminatum (CA).Methods Flow cytometry was employed to study the expression of cytokines IL-2,-12,INF-?and IL-4 in CD8~+ T lymphocytes in the peripheral blood of 60 patients with CA and 20 healthy controls.Results The percentage of CD8~+ T lym- phocytes producing IL-2,IL-12 and IFN-?were significantly lower in CA patients than that in healthy con- trols (P
