Stability of Epigallocatechin Gallate Solid Powder
- VernacularTitle:表没食子儿茶素没食子酸酯固体粉末的稳定性考察
- Author:
Zhen GUO
;
Ren HUANG
;
Min WANG
;
Jiana SHEN
;
Yu'E WU
;
- Publication Type:Journal Article
- Keywords:
Epigallocatechin gallate;
Solid powder;
HPLC;
Stability
- From:
China Pharmacy
2007;0(25):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To investigate the stability of epigallocatechin gallate ( EGCG) powder. METHODS: The content of the sample was determined by HPLC, and the factors affecting the stability of EGCG were studied according to the related guideline stated in China Pharmacopeia. RESULTS: The linear range of EGCG was 7. 76～ 77. 6? g? mL- 1( r=0. 999 9) , with average recovery at 101. 29% ( RSD=0. 76% ) . Exposed to strong illumination, high temperature and high humidity, the color of EGCG powder suffered variant degree of change, but its content experienced no marked change, and no new degraded substances was noted. CONCLUSION: EGCG powder had a sound stability.
