Expression of Cdx2 and MUC2 in reflux esophagitis barrett's esophagus and esophageal adenocarcinoma
- VernacularTitle:Cdx2和MUC2在反流性食管炎、Barrett食管和食管腺癌中的表达
- Author:
Shu LI
;
Bang-Mao WANG
;
Jie ZHANG
;
We-Li FANG
;
- Publication Type:Journal Article
- Keywords:
Esophagitisreflux;
Barrett'sesophagus;
Esophagealcancer;
Cdx2;
MUC2
- From:
Chinese Journal of Digestive Endoscopy
1996;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective In order to investigate the relationship among reflux esophagitis,Barrett's e- sophagus and esophageal adenocarcinomas,the expressions of Cdx2 and MUC2 gene were studied.Methods Using immunohistochemistry,the expressions of the Cdx2 and MUC2 were detected in the esophageal mu- cosa of 30 patients with reflux esophagitis,18 patients with Barrett's esophagus and 25 patients with esopha- geal adenocareinoma.Results The positive rate and staining intensity of Cdx2 and MUC2 expressions in re- flux esophagitis,Barrett's esophagus and esophageal adenocarcinoma were significantly higher than those in normal esophageal mucosa(P
