Ciliary neurotrophic factor in the regeneration of facial nerve
- VernacularTitle:睫状神经营养因子对面神经损伤的修复作用
- Author:
Zhijun ZHANG
;
Bingqing GAO
;
Chuanyu LIANG
;
Zhigang LIAO
;
Jianguo XU
;
Yafeng LIU
- Publication Type:Journal Article
- Keywords:
Ciliary Neurotrophic Factor;
Facial Nerve Injuries;
Nerve Regeneration
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study the role of ciliary neurotrophic factor(CNTF) in the generation of facial nerve.METHODS Twenty adult New Zealand rabbits' bilateral super buccals of facial nerves were transected and connected with silicone tube.CNTF was injected into a random side of silicone tube and normal saline in the other.At four and eight weeks after the operation, both the CNTF group and the SAL group underwent electrophysiology test and histopathology as well as quantity analysis.RESULTS Four weeks later, both CNTF and SAL group failed in eliciting muscular excitement upon stimulation; T-test showed a signifi-cant difference(P
