Study on the Immunoregulation Effect of Astragalus Polysaccharides Combining with Total Ginsenoside
- VernacularTitle:黄芪多糖与人参总皂苷联用的免疫调节作用初步研究
- Author:
Shanyu ZHANG
;
Huishun PIAO
;
Ying'Ai SHEN
- Publication Type:Journal Article
- Keywords:
Astragalus polysaccharides;
Total ginsenoside;
T cell;
Immune function
- From:
China Pharmacy
2005;0(21):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To observe the effects of astragalus polysaccharides(APS) combining with total ginsenoside (TG) on the proliferation of T cells in peripheral blood of healthy adults and on the immune function of mice after treatment with cyclophosphamide (CY) . METHODS: The proliferation rate of T cells in peripheral blood was detected by methyl thia-zolyl tetrazolium(MTT) colorimetric analysis; the weight of immune organs such as spleen and thymus etc. in mice were detected. RESULTS: The proliferation of T cells in human peripheral blood could be enhanced if the concentration of APS remained within 25-100?g/ml and that of TG remained within 5-20?g/ml; the proliferation rates were 102.3%-141.1% and 113.9%-163.1% , respectively; the figure stood at 262.3%-383.0% when APS and TG used in combination. The spleen indexes of APS group and the APS plus TG group increased significantly vs. the CY group(P
