Investigation on Weight Variations and Microbial Contaminations of5Tablets Broken off with Hands
- VernacularTitle:对掰分药片重量差异及微生物污染的考察
- Author:
Ying'Er DING
;
Dongping ZHANG
;
Minli MAO
;
- Publication Type:Journal Article
- Keywords:
Drugs broken off with hands;
Weight variation;
Microbial contamination
- From:
China Pharmacy
2005;0(19):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To improve medication safety and efficacy.METHODS:5different tablets broken off with hands were investigated with respect to weight variations and microbial limits by reference to Chinese Pharmacopeia.RESULTS:The5kinds of tablets broken off with hands were not in conformity with Chinese Pharmacopeia with respect to weight variation and which involved different degrees of microbial contaminations.CONCLUSION:It is recommended that pharmaceutical enter?prises should add more dosage forms of standard drugs that suitable for the use of children,women,the aged and particular patients.If the separately packaged drugs must be broken off with hands,aseptic method should be applied in which the drugs were broken off by the pharmacists on the sterile air bench before being separately packed with sterilized plastic pouches(which were sterilized with anprolene),and which should be administered to the patients for taking during the same day.
