Randomized Double-Blind Controlled Clinical Trial of TCM Treatment for 68 Girls with Sexual Precocity
- VernacularTitle:中医药治疗女童性早熟68例随机双盲对照试验
- Author:
Jian YU
;
Yumin SHI
;
Depei CAI
;
- Publication Type:Journal Article
- Keywords:
Puberty,precocity/TCM therapy
- From:
Journal of Traditional Chinese Medicine
1993;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare therapeutic effects of Chinese medicine prescriptions for nourishing Yin to purge pathogenic fire,and prescriptions for relieving the depressed liver in treatment of sexual precocity of girls.Methods:The girls with sexual precocity were divided with random,double blind and control methods into a treatment group treated with the prescription for nourishing Yin to purge pathogenic fire,Zaoshu No.Ⅱ,and a control group treated with the prescription for relieving the depressed liver, Xiaoyao Pill.The medicines were given with double blind and double simulated methods.The mammary nucleus index,mammary Tanner phasing,cumulative scores of TCM syndromes,B type ultrasonography(volume of the uterus,ovary,the biggest follicle diameter),change of bone age were followed up and compared before and after treatment in the two groups.Follow-up was completed in 132 cases.Results:The treatment group in the mammary nucleus index,mammary Tanner phasing,decrease of cumulative scores of TCM syndromes after treatment was better than the control group(P0.05).Conclusion:Chinese medicine for nourishing Yin to purge pathogenic fire,Zaoshu No.Ⅱ,in therapeutic effect for treatment of sexual precocity of girls is better than the Chinese medicine for relieving the depressed liver,Xiaoyao Pill.
