Effects of Yangyin Qingre Decoction on Expression of Adhesion Molecular and Lupus Index in the Patient of Systematic Lupus Erythematosus
- VernacularTitle:养阴清热煎剂对系统性红斑狼疮患者黏附分子表达及狼疮损伤指数的影响
- Author:
Aiping CHEN
;
Peihua XIONG
;
Fumin LI
- Publication Type:Journal Article
- Keywords:
Lupus erythematosus,systematic/TCM therapy;
@ Yangyin Qingre Decoction;
@ Adhesion molecule
- From:
Journal of Traditional Chinese Medicine
1993;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study on the mechanism of Chinese medicine in treatment of systematic lupus erythematosus(SLE)and to observe long-term therapeutic effect of Chinese medicine on damage of organs in SLE.Methods:51 cases in-patients and out-patients of SLE from 1999 to 2003 were randomly divided into a treatment group treated with integrated Chinese medicine and western medicine and a control group treated with simple western medicine.Serum intracellular adhesion molecule-1(ICAM-1),adhesion molecule-3(ICAM-3),P-selectin and SLE injury index(SLICC/ACRDI)before and after treatment were observed.Results: ICAM-1,ICAM-3 and P-selectin in the patient of SLE were significantly increased as compared with those in normal persons. After treatment,ICAM-1 and P-seleetin in the treatment group decreased significantly as compared with those control group.The cumulative score of SLE injury index in treatment group was more stable and increased significantly in control group compared with that before treatment.Conclusion:The integrated treatment of Chinese medicine and western medicine with Yangyin Qingre Decoction has significant inhibiting action on the high expression of serum adhension molecule and has significant protective and repairing actions on the injury of organs in the patient of SLE.
