Protective Action of Ultramicro-powder of Rhizoma Gastrodiae on Nerves in the Rat of Cerebral Ischemia-Reperfusion Injury
- VernacularTitle:天麻超微粉对大鼠脑缺血再灌注损伤的神经保护作用
- Author:
Tao TAO
;
Kebin ZENG
;
Changlin HU
;
- Publication Type:Journal Article
- Keywords:
Cerebral ischemia/TCM therapy;
Reperfusion injury/TCM therapy;
@Ultramicro-powder of Rhizoma Gastrodiae
- From:Journal of Traditional Chinese Medicine
1993;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore protective action of ultramicro-powder of Rhizoma Gastrodiae on nerves in the rat of Cerebral ischemia- reperfusion injury.Methods:The local ischemia-reperfusion injury at model was established by cerebral ischemia for 2 hours and reperfusion for 24 hours.HE staining,2,3,5-triphenytetrazolium(TTC)staining,immunohistochemical methods were respectively used to investigate pathological changes of brain slices,the size of cerebral infarction and nervous cell apoptotic relative proteins Bcl-2,Bax expression after treatment with ultramicro-powder of Rhizoma Gastrodiae.Results:(1)Ultramicro-powder of Rhizoma Gastrodiae could reduce the size of cerebral infarction.When the low,middle and high dose groups were compared with the ischemia group there were significant differences(P
