Effects of Shenkui Decoction on Proliferation of Ovarian Cancer Fresh Parenchymatous Tumor Cells and Ovarian Cancer Cell Line Tyk-nu Cells
- VernacularTitle:参葵汤对卵巢癌患者新鲜实体瘤细胞及细胞株Tyk-nu细胞增殖的影响
- Author:
Jun ZHANG
;
Jianxin CHENG
;
Baoen SHAN
- Publication Type:Journal Article
- Keywords:
Ovarian cancer/TCM therapy;
Cell division/drug action;
@Shenkui Decoction
- From:
Journal of Traditional Chinese Medicine
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe effects of Shenkui Decoction on proliferation of ovarian cancer cell.Methods:The Shenkui Decoction- containing rat serum was prepared by using TCM serum pharmacological method,and effects of the drug containing serum on proliferation of ovarian cancer fresh parenchymatous tumor cells were investigated with 3H incorporation method,and effects of the drug-containing serum on proliferation of ovarian cancer cell line Tyk-nu cells were investigated by flow cytometry,cellular activity assay,cellular growth curve assay and cell colony formation rate assay.Results:The drug containing serum could inhibit proliferation of both fresh parenckymatous tumor cells and ovarian cancer cell line Tyk-nu cells,and the inhibitory rate raised with the increase of drug-containing serum content.Conclusion:The Shenkui Decoction-containing rat serum can inhibit proliferation of ovarian cancer fresh parenchymatous tumor cells and ovarian cancer cell line Tyk-nu cells.
