Expressions and clinical significance of multidrug resistance associated protein gene (MRP) and lung resistance protein gene (LRP) in hepatocellular carcinoma (HCC)
- VernacularTitle:多药耐药相关蛋白基因、肺耐药蛋白基因在肝细胞癌中的表达及临床意义
- Author:
Bailin WANG
;
Haiyan YANG
;
Shuping ZHAI
;
Xiaoping CHEN
;
Yong ZHONG
;
Qingye ZHANG
;
Lei MENG
- Publication Type:Journal Article
- Keywords:
LIVER NEOPLASMS/pathol;
HEPATOMA/pathol;
GENES EXPRESSION;
MULTIDRUG RESISTANCE;
ASSOCIATED PROTEIN GENE;
LUNG RESISTANCE PROTEIN GENE
- From:
Chinese Journal of General Surgery
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expressions and significance of MRP and LRP in HCC. Methods The expressions of two genes were examined in three tissues (54 cases of HCC, 24 para cancer and 12 posthepatitis cirrhosis tissues) by SP immunohistochemical and PCR techniques. Results MRP and LRP were expressed in three tissues, with significantly higher rates in HCC than others (P
