Effects of Recipes for Tonifying and Supplementing on Apoptosis of Splenocytes in Mice of Injected by Cyclophosphamide
- VernacularTitle:补益方抗环磷酰胺造模小鼠脾细胞凋亡作用的研究
- Author:
Dongqing XU
;
Mingyan WANG
;
Fengming ZHAO
;
- Publication Type:Journal Article
- Keywords:
Apoptosis/drug action;
spleen/drug action;
@tonifying and supplementing recipes
- From:
Journal of Traditional Chinese Medicine
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study effects of 5 recipes for tonifing and supplementing on apoptosis and splenocytes in mice treated with cyclophosphamide.Methods:Apoptosis and cellular cycles of splenocytes were detected by flowcytometric analysis.Results:Sijunzi Decoction,Liuwei Dihuang Pill,Shengmai Powder,Jingui Shenqi Pill could antagonize the decline of proliferation induced by cyclophosphamide,and Sijunzi Decoction and Liuwei Dihuang Pill could resist the apoptosis of splenocytes caused by cyclophosphamide;and the recipes all could inhibit atrophy of the spleen induced by cyclophosphamide Conclusion:The 5 recipes for tonifying and supplementing all can improve the injury of the spleen induced by cyclopbosphamide in varying degrees,Sijunzi Decoction and Liuwei Dihuang Pill being the best.
