Experimental study on the use of ~(103)Pd radioactive stent in the prevention of post-traumatic bile duct stricture in dogs
- VernacularTitle:~(103)钯支架预防犬胆管损伤后狭窄的实验研究
- Author:
Guijin HE
;
Hong ZHANG
;
Shuhe XU
;
Xianwei DAI
;
Weiguo JIANG
;
Hong GAO
- Publication Type:Journal Article
- Keywords:
BILE DUCTS/inj;
BILE DUCTS STENOSIS/prev;
STENTS
- From:
Chinese Journal of General Surgery
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the preventive effects of 103 Pd radioactive stent on stenosis after bile duct injury in dogs.Methods Twelve healthy dogs (15～20kg) were randomly divided into 103 Pd radioactive stent group (n=6) and control group (n=6). Immediately after balloon dilatation injury to the bile duct, the 103 Pd radioactive stent(experiment group) or the ordinary stent(control group) was positioned into the target segment. The dogs were killed one month later. The injured bile duct segments were dissected free from the dogs, and were examined radionucleonically, immunohistochemically and pathologically. Muscular proliferation area and lumen area were determined by computer assisted picture analysis system. Results In the control group, 30 days after ductal injury, the mucosa of the bile duct was fractured, the mucosa was proliferated and the lumen stenosed.Compared with the control group, 103 Pd radioactive stent significantly reduced muscular proliferation area (P
