Effects of Neurohumoral Activity and Cytokines From Differen Dose of Bisoprolol in Chronic Systolic heart Failure
- VernacularTitle:不同剂量比索洛尔对心力衰竭患者神经内分泌及炎症细胞因子的影响
- Author:
Hongman HUANG
;
Mingcheng ZHOU
;
Qian XU
;
Junbo GE
;
Yinhua HE
;
- Publication Type:Journal Article
- Keywords:
Chronic heart failure;
Bisoprolol;
Neurohumoral activity;
Cytokines
- From:
Chinese Circulation Journal
2004;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objec ive: o inves iga e he effec s of differen dose of bisoprolol on neurohormonal ac ivi y,cy okines,cardiac func ion,cardiac dea h in chronic sys olic hear failure pa ien s Me hods: One hundred and wen y chronic hear failure pa ien s were randomly divided in o large dose group (average 8 5? 1 2 mg) and small dose group (average 3 5?1 2 mg) he changes of norepinephrine (NE) ,angio ensionⅡ (AngⅡ) ,aldos erone (Ald) ,endo helin (E ) ,in erleukin 6 BF (IL 6) , umour necrosis fac or ? ( NF ?) Q ,plasm rennin ac ivi y (PRA) ,cardiona rin (ANP) ,brain na riure ic pep ide (BNP) ,cardiac func ion,cardiac dea h were observed Resul s:Af er rea men , he hear ra e were decreased in wo groups, p
