Detection of circulating hepatocellular carcinoma cells with SSX gene mRNA as tumor marker
- VernacularTitle:以SSX基因mRNA作为肿瘤标志物检测循环中的肝癌细胞
- Author:
Zengan WU
;
Xisheng LENG
;
Dongcheng MOU
;
Jirun PENG
;
Li ZHAO
;
Tao LI
- Publication Type:Journal Article
- Keywords:
Hepatocellular carcinoma;
Reverse transcriptase polymerase chain reaction;
SSX gene
- From:
Chinese Journal of General Surgery
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
0 05) However, the positive expression of SSX genes in the PBMC had close correlation with prognosis of HCC patients Metastasis and/or recurrence took place in 50% (8 out of l6) patients with positive expression of SSX genes in their PBMC,while only 10 5% (2 out of l9) patients with negative expression of SSX genes in their PBMC developed metastasis and/or recurrence ( P =0 028) Conclusion SSX genes mRNA may be used as specific tumor markers for the detection of the circulating HCC cells