Effect of maternal diabetes mellitus during pregnancy on brain devel opment of the offspring
- VernacularTitle:母亲孕期糖尿病对子代脑发育影响的研究
- Author:
Lixia SUN
;
Congle ZHOU
;
Hongmei WANG
;
Huixia YANG
;
- Publication Type:Journal Article
- Keywords:
Diabetes,gestational;
Infant, newborn;
Brain;
Ultrasonography
- From:
Chinese Journal of Perinatal Medicine
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of maternal diabetes during pregnancy on brain deve lopment of filial generation. Methods Cerebral gyri width of lobus frontals was measured in 79 infants of pregnant diabetic mother by ultrasound and the parameters were compared with 108 infants of non diabetic mother. We analyzed the relationship between the variation of cerebral gyri width and the diabetic control of the mothers. Brain development status in neonates with diabetic mothers was observed. Results Cerebral gyri width were significantly wider in the full term infants of diabetic mother (1.006?0.102)cm than that of the infants of non diabetic mother (0.859?0.087)cm. This was more obvious in the gyrus frontals superior and initial section[(1.167 ?0.197)cm vs (0.956 ? 0.123) cm]( P 0.05). Conclusions Maternal diabetes in pregnancy may result in filial generation brain immaturity. Cerebral ultrasound can be used to measure the cerebral gyri width.
