Hepatic dysfunction during chemotherapy in breast cancer patients with positive HBsAg
- VernacularTitle:化疗对HBsAg阳性乳腺癌患者肝功能的影响
- Author:
Chunying ZHAO
;
Jingling CHENG
;
Qi FANG
;
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Drug therapy, combination;
Hepatitis B virus;
Hapatic damage
- From:
Chinese Journal of General Surgery
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of chemotherapy on hepatic function in breast cancer patients with chronic hepatitis B virus (HBV) infection Methods In this study, 98 breast cancer patients received two to six courses of standard chemotherapy, alterations in hepatic function and blood HBV DNA level were measured and clinical symptom was observed Results (1) After two courses of chemotherapy, hepatic damage was observed in 36 84 % and 13 33% respectively in HBsAg positive and negative breast cancer patients ( P