The expression and localization of neurokinin-3 receptor in pancreatic carcinoma
- VernacularTitle:胰腺癌组织中神经激肽3受体的表达及组织学定位
- Author:
Xin SHI
;
Nairong GAO
;
Qingming GUO
;
Mingdong HUO
;
Wenhao TANG
;
- Publication Type:Journal Article
- Keywords:
Pancreatic neoplasms;
Receptor, neurokinin-3;
Gene expression
- From:
Chinese Journal of General Surgery
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of neurokinin 3 receptor (NK 3R) in normal pancreas and pancreatic cancer, and to study the localization of this receptor in pancreatic cancer Methods The expression of NK 3R mRNA was investigated using reverse transcription polymerase chain reaction (RT PCR) in normal pancreas and pancreatic cancer tissues The protein level of NK 3R was investigated by Western blot Immunohistochemistry was used to localize expression site of NK 3R Results NK 3R mRNA was overexpressed in pancreatic cancer tissue when compared with normal pancreas NK 3R protein was 1 1?0 5 in normal pancreas and 14 6?3 6 in pancreatic cancer, P
