Prevention and treatment of acute renal failure (ARF) following orthotopic liver transplantation
- VernacularTitle:肝移植术后急性肾功能衰竭七例的防治
- Author:
Chuanyong ZHANG
;
Jun MA
;
Xiaosong CHEN
;
Xiaomin SHI
;
Wenyuan GUO
;
Guoshan DING
;
Zhiren FU
- Publication Type:Journal Article
- Keywords:
Liver transplantation;
Kidney failure, acute;
Postoperative complications;
Drug therapy
- From:
Chinese Journal of General Surgery
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevention and treatment of acute renal failure (ARF) following orthotopic liver transplantation(OLT).MethodsClinical data of 51 patients who underwent liver transplantion consecutively between October 2001 and April 2003 were analyzed retrospectively. Results Preoperatively 9 out of 51 patients had suffered renal dysfunction (Cr≥132 ?mol/L or BUN≥18 ?mol/L), ARF developed in 7 cases within one week postoperatively. Kidney function recovered to normal in 6 cases in 3 to 6 days after administration of vasoactive drugs (dopamine) and daclizumab (Zenapax). One patient failing to response needed hemodialysis for 11 days before his kidney finally functioned. Conclusions The etiology of ARF following OLT is multifactorial, with preoperative, intraoperative and postoperative factors being involved. Individually applied immunosuppressant, improving renal perfusion, and hemodialysis were important for the recovery of kidney function.
