The hemostatic role of human thrombin:a randomized controlled multicenter study
- VernacularTitle:人凝血酶在手术中止血作用的随机对照和多中心临床研究
- Author:
Mingwei ZHU
;
Jinduo CAO
;
Xueguang ZHU
;
Sanguang HE
;
Delin QI
;
Junmin WEI
;
Guodong YE
- Publication Type:Journal Article
- Keywords:
Hemostatics;
Case-control studies;
Thrombin;
Surgical procedures,operative
- From:
Chinese Journal of General Surgery
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo evaluate the hemostatic effect of human thrombin in surgery.Methods A prospective, randomized, controlled and multicenter study was designed to evaluate the hemostatic effect of human thrombin on abdominal operation incision (96 cases) and liver wound (40 cases). Human thrombin was insufflated topically in study group, with 0 9% NS as control. Results The average hemostatic time of abdominal incision in study group was (104?70) s, hemorrhagic volume per square unit was (0 4?0 3)g/cm 2, in liver wound the average hemostatic time was (106?78) s, the hemorrhagic volume per square unit was (1 0?0 7) g/cm 2, the difference was all statistically significant ( P
