The transcription factor Egr-1 and the lung diseases
- VernacularTitle:转录因子Egr-1及其在肺病变中的研究进展
- Author:
Ling CHU
;
Qing-Fu ZENG
;
- Publication Type:Journal Article
- Keywords:
Genes,immediate-early;
Transcription factors;
Lung diseases
- From:
Chinese Journal of Pathophysiology
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Egr-1 is an important transcription factor, which regulates at least 30 kinds of gene expression. Egr-1 couples extracellular signals to long-term responses by altering expression of Egr-1 target genes. So egr-1 can directly or indirectly affect cell differentiation,apoptosis,immune response,injury and repair. This article reviewed the progress in Egr-1 and the lung disease.