Exclusion of 15 Short Tandem Repeat Markers in Duo Paternity Testing
- VernacularTitle:15个STR在单亲亲子鉴定中的排除分析
- Author:
Dejian LU
;
Qiuling LIU
;
Huiling LU
;
Lixian CHEN
;
- Publication Type:Journal Article
- Keywords:
Forensic physical evidence;
Probability of exclusion;
STR mutation;
Duo
- From:
Chinese Journal of Forensic Medicine
2002;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective Estimate the paternity exclusion probability for 15 short tandem repeats (CODIS set plus Penta D and Penta E) in duo paternity tests. Methods 644 random individuals were paired to con-struct 207046 fictitious duo families. Cases of non-exclusion or with only one exclusionarylocus were count-ed. Results 27 cases could not be excluded by the 15 STR loci. The combined probability of exclusion was 0.999869. Number of cases showing only one exclusionary locus was 384 (0.185%). Conclusion To con-firm relationship in duo cases with only 15 STRs should be careful. Extensive genetic markers is needed to discriminate one locus exclusion or mutation.
