Study on Mechanism of Intestinal Absorption of Protocatechualdehyde in Rats
- VernacularTitle:原儿茶醛大鼠小肠吸收机理的研究
- Author:
Min JIANG
;
Enjuan ZHANG
;
- Publication Type:Journal Article
- Keywords:
protocatechualdehyde;
intestinal absorption;
HPLC
- From:
China Pharmacy
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To study the mechanism of intestinal absorption of protocatechualdehyde .METHODS: Using invivo rat intestinal absorption model and HPLC, the apparent small intestine absorption rate of protocatechualdehyde was mea-sured. RESULTS: Under low, medium and high concentrations of drug, the apparent small intestine absorption rates of proto-catechualdehyde were 1.1 341/h, 1.1 637/h and 1.0 847/h respectively .CONCLUSION: The protocatechualdehyde absorptionmechanism is passive diffusion.