Prognostic value of angiogenesis in breast carcinoma and its relationship with p53 expression
- VernacularTitle:血管生成对乳腺癌的预后价值及与p53表达的关系
- Author:
Hongyuan LI
;
Kainan WU
;
Shengchun LIU
;
- Publication Type:Journal Article
- Keywords:
BREAST NEOPLASMS/pathol;
MICROVESSEL DENSITY;
PROGNOSIS;
ONCOGENE PROTEIN p53
- From:
Chinese Journal of General Surgery
1994;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the role of angiogenesis in the prognosis of breast carcinoma and its relationship with p53 expression and ER statue in 59 cases of breast cacinoma. Methods Factor Ⅷ related antigen (FⅧ RA) and p53 were evaluated by immunohistochemical staining,and the microvessel endothelial area (MEA) of tumor microvessels was detected by computer aided image analysis system. Results (1) The expression of MEA significantly increased with tumor size and histologic grade(P
