The expression pattern of pleiotrophin in colorectal malignancy
- VernacularTitle:多效蛋白在大肠癌恶性化过程中的作用
- Author:
Yuan GAO
;
Jiren YU
;
Shusen ZHENG
;
Min ZHANG
;
- Publication Type:Journal Article
- Keywords:
Retroviridae;
Colorectal neoplasms;
Transforming growth factor beta
- From:
Chinese Journal of General Surgery
1994;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo study the expression of pleiotrophin (PTN) in colorectal cancer and its impact on the malignancy.MethodsRT PCR and immunoperoxidase staining were applied on the resected samples.ResultsPTN mRNA was expressed in 18 cases of 24 colorectal cancer tissues and 18 cases of 19 adjacent normal tissues. PTN protein was also found expressed in stroma, but the expression rate was higher in colorectal cancer tissues (34%) than in adjacent normal tissues (9%, P
