Oxytocin receptor and tumor
- VernacularTitle:催产素受体与肿瘤
- Author:
Ruiyao CUI
;
Yongjiu WANG
;
Zhendong YOU
;
- Publication Type:Journal Article
- Keywords:
Receptor,oxytocin;
Neoplasmas;
Signal transduction
- From:
Chinese Journal of Pathophysiology
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Oxytocinreceptor(OTR)isamemberofG -proteincoupledreceptor ,whichhasbeen foundinmanytumorsandcancercelllines .Manystudiesrevealedoxytocin(OT)mayinhibitthetumorand cancercellgrowthandproliferation ,butthemechanismofthisinhibitionisnotwellknown .Someexperiments indicatedcAMP -PKAsystemparticipatesinthesignaltransductionthatoxytocininhibitsthecancercellpro liferation .However ,otherexperimentsshowedthesignaltransductionforoxytocinintheHs5 78Tcarcinosaco macellisthesameasthatinthenormalcells .Inthisreview ,therelationshipbetweenOTRandtumorsare summarized . [
