A Case of Neurotized Nevus with Sclerotic Fibroma-like Change.
- Author:
Hyae Joo JEON
1
;
Seong Hyun KIM
;
Kyu Kwang WHANG
;
Jeong Hee HAHM
Author Information
1. Department of Dermatology, College of Medicine, Ewha Womans University, Seoul, Korea. JHHAHM@mm.ewha.ac.kr
- Publication Type:Case Report
- Keywords:
Intradermal nevus;
Neurotized nevus;
Sclerotic fibroma
- MeSH:
Abdomen;
Biopsy;
Collagen;
Dermis;
Female;
Humans;
Hyalin;
Melanocytes;
Middle Aged;
Nevus*;
Nevus, Intradermal;
Skin
- From:Korean Journal of Dermatology
2007;45(10):1074-1077
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of neurotized nevus with a sclerotic fibroma-like change in a 60-year-old female patient, who presented with a brown colored pedunculated nodule on the upper quadrant of the abdomen. The skin biopsy revealed a well-circumscribed, non-encapsulated nodule in the reticular dermis, which consisted of hypocellular hyalinized collagen bundles separated by clefts mixed with nevus cells. Nevus cells are small with a spindle appearance and contain Meissner corpuscle-like structures called nevic corpuscles. We suggest that a sclerotic fibroma-like change is an evolutionary end-point of a pre-existing lesion. This is supported further by the fact that neuroid change in the intradermal nevus represents the end stage of maturation of melanocytes of the nevi.
