Serum Levels of Soluble Intercellular Adhesion Molecule-1(sICAM-1) in Women with Pregnancy-induced Hypertension (PIH) and Its Roles in the Pathogenesis of PIH
- VernacularTitle:妊娠高血压综合征患者血清sICAM-1含量测定及其在妊高征发病中的作用
- Author:
Yajun XIA
;
Tong LIU
;
Tao MENG
;
Al ET
- Publication Type:Journal Article
- Keywords:
Pregnancy complications,cardiovascular;
Hypertension;
so luble Intercellular ad- hesionmolecule-1;
Interleuk in-1;
Tumor necrosis factor
- From:
Chinese Journal of Perinatal Medicine
1998;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the roles of soluble intercellular adhesion molecule 1(sICAM 1) in the pathogenesis of pregnancy induced hypertension (PIH). Methods Serum levels of sICAM 1 were measured by enzyme linked immunosorbent assay(ELISA) in 65 women with PIH (PIH group : 15 mild PIH, 24 moderate PIH and 26 severe PIH) and 25 normal pregnant women (control group). The serum levels of IL 1? and TNF ? were measured by chemiluminescent ELISA at the same time. Results Serum concentrations of sICAM 1 were significantly higher ( P