Expression of Vascular Cell Adhesion Molecule-1(VCAM-1) in Placenta of Pregnancy Induced Hypertension Complicated by Fetal Growth Restriction
- VernacularTitle:妊娠高血压综合征合并胎儿生长受限胎盘组织血管细胞粘附分子1的表达
- Author:
Zhijian WANG
;
Yanhong YU
;
- Publication Type:Journal Article
- Keywords:
Pregnancy complications, cardiovascular;
Hypertension;
Fetal growth retardation;
Vascular cell adhesion molecule 1;
Immunohistochemistry
- From:
Chinese Journal of Perinatal Medicine
1998;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the role of vascular cell adhesion molecule 1 (VCAM 1) in pathogenesis of pregnancy induced hypertension (PIH) complicated by fetal growth restriction (FGR). Methods The placenta samples were collected from 30 pregnant women with PIH complicated by FGR, 28 FGR patients without PIH and 30 normal pregnant women. Immunohistochemical analysis was used to demonstrate the positive expression of VCAM 1 in placenta vascular endothelium and syncytiotrophoblast of these samples. Results In placentas of PIH complicated by FGR (80%),expression of VCAM 1 in the decidual vascular endothelium was significantly higher than those without PIH (25%) and normal placentas (15%)( P
