Treatment of severe acute pancreatitis patients with multiple organ dysfunction by combination of somatostatin,growth hormone and hypocaloric parenteral nutrition
- VernacularTitle:生长激素和生长抑素联合低热量肠外营养治疗SAP并发MOD
- Author:
Quanyan LIU
;
Zhisu LIU
;
Xiaoguo ZHANG
;
Tiyong YANG
;
Yueying YUANG
;
- Publication Type:Journal Article
- Keywords:
PANCREATITIS/compl;
MULTIPLE ORGAN DYSFUNCTION/compl;
GROWTH HORMONE/ther use;
SOMATOSTATIN/ther use;
PARENTERAL NUTRITION
- From:
Chinese Journal of General Surgery
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of combination of growth hormone(GH),somatostatin(ST) with hypocaloric parenteral nutrition(HPN) on SAP patients with MOD. Methods forty one cases of SAP complicated with MOD were randomedly divided into control group (20 cases) and experiment group (21 cases). In experiment group ,total calories and nitrogen were given 62.9～83.9kJ/(kg?d) and 0.10～ 0.12g/(kg?d). lipid calorie was supplied in less than 40 percent of the total energy.GH was percutaneously injected for 7d and ST was intravenously injected for 7～14d. Control group was given TPN only.Serum albumin, pre albumin, transferring,CRP,total lymphocyte count(TLC), urea nitrogen, nitrogen balance and serum TNF ?, IL 1,IL 6 level were determined before treatment and on the day 7 after treatment. Results After treatment, serum albumin and pre albumin and transferring increased significantly (P
