Influence of obstructive jaundice on macrophage activity and bacterial translocation
- VernacularTitle:梗阻性黄疸对巨噬细胞活性和细菌移位的影响
- Author:
Fu QIU
;
Huihuan TANG
;
Xinsheng LU
;
- Publication Type:Journal Article
- Keywords:
CHOLESTASIS/physiopothol;
MACROPHAGE ACTIVATION;
BACTERIAL TRANSLOCATION
- From:
Chinese Journal of General Surgery
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influence of bile duct ligation ( BDL ) on macrophage ( M ) activity and bacterial translocation in mice . Methods After 7 days of BDL , the levels of serum total bilirubin(TB) , albumin(Alb) , glutamic - oxaloacetic transaminase(AST) , creatinine(Cr) , alkaline phosphatase(ALP) and nitrogen oxide(NO) producted by peritoneal macrophages were measured . The mesenteric lymph nodes were cultured for bacteria . The liver and kidney tissues were histopathologically examined. Results The levels of serum iTB,AST,AKP in BDL group were significantly higher than those in control group(P
