Significance and expression of microvessel density,vascular endothelial growth factor and matrix metalloproteinases 2 in cholangiocarcinoma
- VernacularTitle:胆管癌微血管计数和VEGF及MMP2的表达及其意义
- Author:
Jun ZHOU
;
Huihuan TANG
;
- Publication Type:Journal Article
- Keywords:
BILE DUCT NEOPLASMS/pathol;
MICROVESSEL DENSITY;
VASCULAR ENDOTHELIAL GROWTH FACTOR;
MATRIX METALLOPROTEINASES 2;
NEOPLASM METASTASIS
- From:
Chinese Journal of General Surgery
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between the microvesel density(MVD) ,vascular endothelial growth factor(VEGF) , matrix metalloproteinases 2 ( MMP2 ) with the metastasis, prognosis of cholangiocarcinoma. Methods MVD,expression of VEGF and MMP2 were investigated by means of immunohistochemistry in 45 cholangiocarcinoma tissues and 8 normal bile duct tissues. Results (1)MVD and positive expression rates of VEGF , MMP2 in cholangiocarcinoma tissues were significantly higher than those in normal bile duct tissues ( P
