Expression of cyclooxygenase-2 (COX-2) in hepatocellular carcinoma cell lines
- VernacularTitle:环氧合酶-2在肝癌细胞系中的表达研究
- Author:
Kun WANG
;
Baocai XING
;
Qingyun ZHANG
;
Guangwei XU
;
- Publication Type:Journal Article
- Keywords:
Oxygenases;
Carcin oma, hepatocellular;
Cell lines;
Immunohistochemistry
- From:
Chinese Journal of General Surgery
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of cyclooxygenase-2 in hepatocelluar carcinoma cell lines. Methods RT-PCR and immunocytochemistry were use d to investigate the expression of cyclooxygenase-2 in 6 hepatocellular carcino ma cell lines. Result COX-2 mRNA expression was detected in five of six cell lines, and all six cell lines w ere positive for COX-2 protein expression. Conclusion COX-2 is expressed in hepatocellular carcinoma cell li nes, providing basis for the chemoprevention of hepatocelluar carcinoma.
