Propofol anesthesia with target-controlled-infusion controlled by feedback from BIS
- VernacularTitle:脑电双频谱指数反馈调控异丙酚靶控输注静脉麻醉
- Author:
Meng WANG
;
Xing XU
;
Xinmin WU
;
- Publication Type:Journal Article
- Keywords:
Electroencephalography;
Feedback;
Propofol;
Anesthesia, intravenous;
Target- controlled infusion
- From:
Chinese Journal of Anesthesiology
1994;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective Target-controlIed-infusion(TCI) system makes administration of intravenous anesthetics simpler, more accurate and adjustable. Bispectral index (BIS) is generally accepted as a measurement of depth of sedation and anesthesia. The aim of this study was to evaluate the usefulness of BIS as a feedback control in propofol anesthesia with TCI for patients undergoing laparoscopic cholecystectomy. Methods Forty ASA Ⅰ - Ⅱ patients (12 male, 28 female) aged between 20-70 yr were randomly allocated to one of two groups of twenty each: feedback TCI group and TCI group. In feedback TCI group, BIS value of 50 was set as the control variable. A bolus of 3 ?g?kg-1 fentanyl was given Ⅳ 3 min before induction. The target concentration of propofol was set at 3 ?g?ml-1 throughout anesthesia. Real time BIS, the highest and lowest systolic and diastolic pressure during operation, doses of adjunctive drugs, time for emergence and orientation, awareness during operation and the standardized unit dose of propofol were recorded and compared between groups. Results Total dose of propofol was statistically lower in the feedback TCI group than that in TCI group(P
