Detection of Interleukin-4 andInterferon-? in Patients with Syphilis
- VernacularTitle:梅毒患者单一核细胞体外培养观察白介素-4、?干扰素的变化
- Author:
Xiaoming ZHOU
;
Liyi ZHOU
;
Xingping CHEN
;
- Publication Type:Journal Article
- Keywords:
Syphilis;
Interleukin4;
Interferon-?
- From:
Chinese Journal of Dermatology
1995;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTostudytheroleoffunctionalsubetsofCD4+Tlymphocytesinsyphilis.Methods40casesofsyphilis(20casesofprimaryandsecondarysyphiliseach)enteredinthisstudy,and15normalindividualsascontrols.Theperipheralbloodmononuclearcells(PBMCs)ofpatientswithsyphilisandnormalcontrolswereculturedinvitrowithphytohemagglutinin(PHA)for48hours,andtheTh2cytokineIL-4、Th1cytokineinterferon-?(IFN-?)inthesupermatantweremeasured,thechangesofIL-4,IFN-?ineachstageofsyphiliswereobserved.ResultsTheresultsshowedthattheproductionofIL-4insyphilispatientswasmarkedlyhigherthanthatinnormalcontrols,(P
