An experimental study on the cerebral vascular injury in case of positional asphyxia
- VernacularTitle:体位性窒息对脑血管损伤的实验观察
- Author:
Hualan JING
;
Yuchuan CHEN
;
Zhaohui LI
;
- Publication Type:Journal Article
- Keywords:
Forensic pathology;
Cerebral vascular injury;
Positional asphyxia;
vWF
- From:
Chinese Journal of Forensic Medicine
1987;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective This research aimed to study if the cerebral vascular injury can be caused by the positional asphyxia. Method The brain tissue sections were studied immunohistochemically (SABC method) by using the anti-human von Willebrand Factor (vWF) and anti-human albumin as the first antibody. Results No positive expression of vWF and albumin was found in the cerebral blood vessels of control group. The vivid positive expression of albumin and vWF were observed in the positional asphyxia group. Conclusion The results indicate that the positional asphyxia can result the expression of the vWF in the cerebral vessels and it seems one of the injury markers in the cerebral blood vessels and can be used to probe the mechanism of positional asphyxia.