Effects of preoperative selective gastric arterial chemoembolization on the tumor vasculature in patients with gastric carcinoma
- VernacularTitle:胃癌病人术前选择性动脉栓塞化疗对肿瘤血管的影响
- Author:
Suikang SUN
;
Qingfan PU
;
Lunan YAN
;
Jibao PAN
;
Gaojian CAO
;
Wenzheng WU
- Publication Type:Journal Article
- Keywords:
STOMACH NEOPLASMS/drag ther;
EMBOLIZATON,THERAPEUTIC;
STOMACH NEOPLASMS/blood supply;
INFUSIONS,INTRA ARTERIAL
- From:
Chinese Journal of General Surgery
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of preoperative selective gastric arterial chemoembolization on the tumor vasculature in patients with gastric carcinoma.Methods 40 patients with gastric cancer were divided into two groups :(1)gastric arterial influsion(GAI)group;and (2)gastric arterial chemoembolization(GAE)group.The peripheral vein plasma tumor necrosis factor(TNF ?) and thrombomodulin(TM)were determined before radiologic intervention(RI),and1d,3d after R1;and the gastric vein plasma TNF ? and TM were also determined during operation.The curative surgical resection of gastric cancer was performed between 7 and 10 days after treatment.Stomach histological alterations were observed postoperatively.Results Compared with GAI group ,the plasma TNF ? levels increased markedly at all the time points,and gastric vein plasma TM levels decreased siginificantly in GAE group (P
