Clinical significance of micrometastasis detection in conventional pathologic nonmetastasis lymph nodes of patients with gastric cancer
- VernacularTitle:胃癌阴性淋巴结的微转移检测的临床意义
- Author:
Lianghui SHI
;
Guohai ZHAO
;
Wenbin HUANG
;
- Publication Type:Journal Article
- Keywords:
STOMACH NEOPLASMS/pathol;
LYMPHATIC METASTASIS;
MICROMETASTASIS DETECTION;
NEOPLASM INVASIVENESS
- From:
Chinese Journal of General Surgery
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between lymph node micrometastasis and clinicopathological parameters. Methods Immunohistochemical method was adopted to detect CK19,CK20 and CD44v6 in 509 lymph nodes from 53 cases of gastric cancer, in which, conventional pathological diagnosis showed no lymph node metastasis. Results Micrometastasis was found in 47 lymph nodes (9.2%) of 21cases ( 39.6 %). The incidence of micrometastasis was correlated with the depth of invasion, and the incidence of micrometastasis in PT 3 and PT 4 patients was more than that in PT 1 and PT 2 patients(P