Protective mechanism of adenosine on intestinal barrier function in acute hemorrhagic necrotizing pancreatitis pigs
- VernacularTitle:腺苷对急性出血坏死性胰腺炎肠道屏障功能保护机制的实验研究
- Author:
Shu ZOU
;
Hong SHAO
;
Darong HUANG
;
Fuzhou TIAN
;
Zhiliang YING
;
Xiaojun LI
;
Tao WANG
;
Xiaomei GAO
- Publication Type:Journal Article
- Keywords:
PANCREATITIS/pathol;
?ADENOSINE/pharmacol;
?INTESTINAL BARRIER FUNCTION;
?ANIMALS, LABORATORY
- From:
Chinese Journal of General Surgery
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the protective mechanism of adenosine on intestinal barrier function in acute hemorragic necrotizing pancreatitis (AHNP) pigs; Methods Twelve small pigs were equally devided into two groups randomly after the AHNP model sitted up: (1) AHNP controll group (group A) and adenosine treated group (group B). The intestinal blood flow, intestinal permeability, bacterial culture and endotoxin in portal blood were compared between the two groups in pre and post AHNP. Results (1)The intestinal blood flow was dramatically decreased in group A, and much higher in group B than that in group A at the 8 h, 24 hour and day 7 after ANHP model was setted up (P0.001,P
