Effect of hemihepatectomy on the level of serum thyroxin and insulin
- VernacularTitle:半肝切除手术对血清甲状腺激素、胰岛素水平的影响
- Author:
Jiwei YU
;
Zhe JI
;
Xueli JI
;
Zhibang LIU
;
Zhengzhong ZHOU
;
Peng LI
;
Jian GENG
- Publication Type:Journal Article
- Keywords:
HEPATECTOMY;
?LIVER/metab;
?THYROXIN/blood;
?INSULIN/blood
- From:
Chinese Journal of General Surgery
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the mechanism of serum thyroxin and insulin change after hemihepatectomy. Methods The hemihepatectomy was performed in rabbits, the fasting peripheral blood samples were drawn on the day prior to surgery, and 24 hour, 48 hour, the first week, one month after operation respectively for monitoring the serum thyroxin and insulin.Results The level of TT 3 was (1.93?0.47) nmol/L, TT 4 (53.56?8.4) nmol/L preoperatively. The levels of TT 3 and TT 4 significantly decreased at 24 hour postoperatively, and gradually rose at 48 hour and up to normal levels in the first month postoperatively. The level of insulin rapidly rose immediately after operation, and began to decrease in the first week, and returned to the preoperative level in one month after operation. Conclusions The syndrome of normal thyroid disease and the syndrome of non thyroid disease can occur after hemihepatectomy; and hyperinsulinemia also can occur after hemihepatectomy.
