Current research on pancreatic encephalopathy
- VernacularTitle:胰性脑病的研究现状
- Author:
Chongliang LU
;
Qingzhong HE
;
- Publication Type:Journal Article
- Keywords:
PANCREATITS/compl;
?ACUTE DISEASE;
?BRAIN DISEASES/etio;
?REVIEW CITERATURE
- From:
Chinese Journal of General Surgery
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To introduce the current progress of research on pancreatic encephalopathy(PE). Methods Collecting related articles to make this paper.Results (1) The reported incidence of PE was from 11% to 53%. (2).The main pathogenisis of PE was large quantity of enzymes, which were secreted by the pancreas, entering the blood and crossing the blood brain barrier resulting in brain damage. (3).The demyelination could be seen on the brain pathologically. (4).The main clinical features of PE were temporal confusion, coma and neurasthenic syndrome. (5).The treatments of PE include treating underline disease, trying gabexale mesilate(Foy), a new special enzyme inhibitor, and the symptom control treatment. Conclusions PE is a dangerous complication of pancreatitis with a very bad prognosis. Evaluated myelin basic potein(MBP)may be a early, reliable biochemical parameter for diagnosis of PE. A special enzyme inhibitor Foy may be very useful in treating PE.
