Study on Correlativity of HLA - DQA1 Allelic Gene with Varied TCM Constitution Types in Acute Cerebral Infarction
- VernacularTitle:HLA—DQA1等位基因与急性脑梗塞多种中医体质类型的相关性研究
- Author:
Naiying SHEN
;
Zheng YAN
;
Yu'An JIN
;
Jing HAN
;
Peiying HE
;
Shenwu WANG
- Publication Type:Journal Article
- Keywords:
cerebral infarction/ genetics
- From:
Journal of Traditional Chinese Medicine
1993;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Varied TCM constitutions in the patient of acute cerebral infarction were classifyed by using HLA - DQAl allehc gene to analyze hereditary susceptibility of constitution types and relation among constitution, syndrome and treatment. PCR-SSP technique was used for classification of Yin - deficiency Yang - deficiency, Qi - deficiency, phlegm - dampness and blood stasis constitution in 103 cases of acute cerebral infarction and HLA - DQAl allelic gene was used for gent classification in 99 cases of nomal constituion. Results indicated that HLA -DQA * 0501 gene type in Yin -deficiency constitution was significant higher than that of normal constitution CP
