The relationship of bone marrow micrometastases and nm23 expression in patients with stage-Ⅰ breast cancer
- VernacularTitle:Ⅰ期乳癌骨髓微小癌转移及nm23表达的研究
- Author:
Wenbin GUO
;
Jun LIU
;
Chunfu ZHANG
;
Yuzhong LIU
;
Xijing ZHUANG
;
Yanxia WANG
- Publication Type:Journal Article
- Keywords:
BREAST NEOPLASMS/pathol;
?NEOPLASM METASTASIS/pathol;
?BONE MARROW NEOPLASMS/second;
?BREAST NEOPLASMS/genet;
?GENE EXPRESSION
- From:
Chinese Journal of General Surgery
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship of bone marrow micrometastases(BMM) with nm23 expression of breast cancer(BC) in patients with stage Ⅰ BC. Methods BMM and nm23 expression of carcinoma tissue in 52 cases of stage Ⅰ BC were examined by immunohistochemical technique with monoclonal anti epithelial membrane antigen(anti EMA) and nm23 H1. Results BMM was observed in 10 of 52 patients(19.2%). In the group of poor differentiated cancer, the positive rate of BMM was significantly higher than that in well differentiated cancer(P
