Chinical research on the perioperative application of propranolol in patients with hyperthyroidism
- VernacularTitle:甲亢病人围手术期应用心得安的临床研究
- Author:
Yuexian GUO
;
Xiuli WANG
;
Zengan WU
;
Ping LU
;
Jinhua ZHANG
;
Qingyun MENG
- Publication Type:Journal Article
- Keywords:
HYPERTHYROIDISM/surg;
?PROPRANOLOL/ther use;
?PERIOPERATIVE PERIOD
- From:
Chinese Journal of General Surgery
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of propranolol on thyroid hormone in patients with hyperthyroidism after operation. Methods Forty patients with mediate or severe degree hyperthyroidism undergoing operation were randomly divided into four groups according to anesthesia and whether to take propranolol in perioperative period: Group A:propranolol plus general anesthesia; Group B: general anesthesia; Group C:propranolol plus cervical plexus blocking; Group D: cervical plexus blocking. The consecutive changes of T 3, T 4,rT 3 and TSH were measured with radioimmunological assay pre and post operatively. Results The level of serum T 3 in all groups decreased 1～7 days after operation. The decrease in serum T 3 leves was most significant 3～7 days after operation in group A and C, 1～3 days after operation in proup B and D(P
