The Effect of Pulmanory Surfactant on the Incidence of Bronchopulmonary Dysplasia
- VernacularTitle:肺表面活性物质替代治疗对支气管肺发育不良发病的影响
- Author:
Xianqiong LUO
;
Xiaoguang ZHOU
;
- Publication Type:Journal Article
- Keywords:
Pulmonary surfactantss;
Infant, newborn;
Bronchopulmonary dysplasiaD
- From:
Chinese Journal of Perinatal Medicine
2000;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Obiective To explore the effect of pulmanory surfactant on the incidence of bronchopulmonary dysplasia. Methods In a case control study, 25 newborns with NRDS were treated with Exosurf. At the same time, other 25 newbons with NRDS were served as control. The incidence of BPD in two groups was compared. Results The duration of mechanical ventilation and oxygen therapy was shortened in the group treated with PS (13 2?9) days vs (6?4) days, (21?9) days vs (9.3?6) days, respectively The incidence of BPD was decreased from 40% to 20%. Conclusion The duration of mechanical ventilation and oxygen therapy can be shortened in the newbons of NRDS treated with PS, but the decreasing of the incidence of BPD were not confirmed.